They include sudden shortness of breath, chest pain while breathing in or coughing, rapid breathing, rapid pulse, feeling faint or fainting, and coughing up blood. Get immediate medical help if you have symptoms of PE. It occurs when a blood clot (thrombus) in a leg or other body area breaks free and gets stuck in a blood vessel in a lung. PE is a potentially life-threatening complication associated with DVT. Sometimes, a blood clot in a vein can occur with no identifiable risk factor. An inherited disorder on its own might not cause blood clots unless combined with other risk factors. This inherited disorder changes one of the clotting factors in the blood. Some people have DNA changes that cause the blood to clot more easily. If you or someone in your family has had one or both of these conditions, you might be at greater risk of developing DVT. A personal or family history of DVT or PE. ![]() Crohn's disease or ulcerative colitis increase the risk of DVT. Because the heart and lungs don't work well in people with heart failure, the symptoms caused by even a small pulmonary embolism are more noticeable. Heart failure increases the risk of DVT and pulmonary embolism. Some types of cancer treatment also increase the risk of blood clots. Some cancers increase substances in the blood that cause the blood to clot. Smoking affects how blood flows and clots, which can increase the risk of DVT. Being overweight increases the pressure in the veins in the pelvis and legs. Both can increase the blood's ability to clot.
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